Is Your Gut Trying to Tell You Something?

Repair your gut lining naturally with 6,000mg L-Glutamine and soothing botanicals*

Developed by Brenda Watson, CNC

Signs Your Gut Lining May Need Support

Check any symptoms you experience regularly. The more boxes checked, the more your gut may be asking for help.

Bloating after meals
Heartburn or acid reflux
Food sensitivities increasing
Brain fog or fatigue
Skin issues (acne, rashes)
Joint discomfort
Irregular bowel habits
Feeling "off" despite eating well
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Select Symptoms
0 of 8 symptoms selected
Check the symptoms you experience regularly to see personalized guidance.

What Is "Leaky Gut"?

Your intestinal lining is designed to be selectively permeable, letting nutrients through while keeping unwanted particles out. When this barrier becomes compromised, research on intestinal permeability shows that microscopic gaps can allow undigested food particles, toxins, and bacteria to "leak" into the bloodstream, potentially triggering inflammation and a range of uncomfortable symptoms.*

This is where L-Glutamine comes in. As the most abundant amino acid in the body, glutamine serves as the primary fuel source for the cells that line your intestinal wall, helping to support their repair and regeneration.*

Healthy Gut Lining

Tight junctions between cells control what passes through. Nutrients enter; toxins stay out.

Compromised Gut Lining

Gaps in the lining allow unwanted particles to pass through, potentially causing inflammation.*

The Gut Renew Formula

Every serving combines a therapeutic dose of L-Glutamine with five time-honored botanicals selected for their gut-soothing properties.*

L-Glutamine
L-Glutamine
6,000mg per serving

The building block for intestinal cells. Research confirms it serves as primary fuel for gut lining repair and regeneration.*

Aloe Vera
Organic Aloe Vera
Soothing botanical

Soothes and coats the digestive tract. Studies show aloe vera supports intestinal tight junction integrity.*

Marshmallow Root
Marshmallow Root
Organic extract

Research shows its polysaccharides create a protective mucilage layer along the digestive tract for added comfort.*

Ginger Root
Organic Ginger Root
Warming botanical

Calms occasional digestive discomfort and clinical research shows it supports healthy gastric motility.*

DGL Licorice
DGL Licorice Root
Deglycyrrhizinated

Studies show DGL supports stomach and esophageal comfort without the side effects of regular licorice.*

N-Acetyl D-Glucosamine
N-Acetyl D-Glucosamine
Mucosal support

A pilot study found it supports the gut's protective mucosal lining and healthy intestinal barrier function.*

Several of these ingredients, particularly L-glutamine, DGL licorice, and aloe vera, have also been studied for their role in supporting occasional heartburn and acid reflux comfort. For a deeper look at that research, see our guide on probiotics for acid reflux.

Your 4-Week Gut Renewal Journey

Gut lining repair takes time and consistency. Here's what to expect as you support your gut with Gut Renew.*

Week 1
Building the Foundation

L-Glutamine begins fueling your intestinal cells. You're establishing the daily habit of taking Gut Renew on an empty stomach.

Week 2
Soothing Takes Effect

The botanical blend (aloe, marshmallow root, ginger) begins calming occasional digestive discomfort.*

Week 3
Noticeable Comfort

Many people begin noticing improved digestive comfort and fewer symptoms that prompted them to try Gut Renew.*

Week 4 & Beyond
Ongoing Support

Your gut lining has had consistent support for a full month. Many choose to continue daily use for ongoing maintenance.*

Simple Morning Routine

Gut Renew works best on an empty stomach. Here's how to make it part of your morning:

1
Mix
Mix One Scoop

Add one scoop of Gut Renew powder to 8 oz of water. Stir until dissolved.

2
Drink
Drink on Empty Stomach

Take first thing in the morning before eating anything else.

3
Wait
Wait 30 Min, Then Eat

Wait 30 minutes before eating breakfast for optimal absorption.

Choose Your Format

Three formats, same powerful botanical blend. Choose the delivery method that fits your lifestyle.

Best Value
Vital Gut Renew Powder
Gut Renew Powder
30 or 60 servings • Non-flavored
6,000mg
L-Glutamine
5
Botanicals
$39.99+ from $1.33/serving
Shop Powder
Travel-Ready
Vital Gut Renew Stick Packs
Gut Renew Stick Packs
30 single-serve packs • Pre-measured
6,000mg
L-Glutamine
5
Botanicals
$39.99 $1.33/pack
Shop Stick Packs
Easy Swallow
Vital Gut Renew Capsules
Gut Renew Capsules
30-day supply • Vegetarian capsules
1,800mg
L-Glutamine
6
Ingredients
$32.99 $1.10/day
Shop Capsules

Gut Renew + Probiotics: Better Together

Think of your gut like a house. Gut Renew repairs the structure; probiotics fill it with good inhabitants.*

Gut Renew
Gut Renew

Repairs the house. L-Glutamine and botanicals support gut lining integrity.*

+
Probiotics
Vital Flora Probiotics

Fills it with good tenants. Beneficial bacteria support balanced gut flora.*

Frequently Asked Questions

What exactly is "leaky gut"?
"Leaky gut" refers to increased intestinal permeability. When the tight junctions between cells in your gut lining become compromised, particles can pass through that normally wouldn't. This can trigger inflammation and a range of symptoms including bloating, fatigue, food sensitivities, and more.*
How long until I notice a difference?
Everyone's gut is different. Some people notice improvements within the first 1-2 weeks, while for others it may take 3-4 weeks of consistent daily use. We recommend committing to at least 30 days to give your gut lining adequate time for repair and support.*
Can I take Gut Renew with probiotics?
Absolutely! In fact, they complement each other beautifully. Take Gut Renew first thing in the morning on an empty stomach. You can take your probiotic later with a meal or as directed. Gut Renew supports the gut lining while probiotics support the beneficial bacteria living there.*
Why is L-Glutamine important for gut health?
L-Glutamine is the most abundant amino acid in your body and serves as the primary fuel source for enterocytes (the cells that line your intestinal wall). These cells turn over rapidly (approximately every 3-5 days), and glutamine helps support their regeneration and maintenance. At 6,000mg per serving, Gut Renew provides a therapeutic dose.*
Is Gut Renew safe for long-term use?
Yes, Gut Renew is formulated for daily use. Many people use it as part of their ongoing gut health regimen. The ingredients are gentle and well-tolerated. As with any supplement, we recommend consulting with your healthcare provider if you have specific health concerns or are pregnant/nursing.
I have food sensitivities. Is this product safe for me?
Gut Renew is free from GMOs, dairy, yeast, gluten, wheat, soy, tree nuts, shellfish, and sugar. It's also vegan. However, if you have specific allergies or sensitivities, we always recommend reviewing the full ingredient list and consulting with your healthcare provider before starting any new supplement.

Sources

  1. Fasano, A. (2012). "Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications." Clin Gastroenterol Hepatol. PubMed
  2. Rao, R.K. & Samak, G. (2012). "Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions." J Epithel Biol Pharmacol. PMC
  3. Kim, M.H. & Kim, H. (2017). "The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases." Int J Mol Sci. PubMed
  4. Shin, M.R. et al. (2021). "The Role of Processed Aloe vera Gel in Intestinal Tight Junction: An In Vivo and In Vitro Study." J Med Food. PMC
  5. Deters, A.M. et al. (2010). "Aqueous extracts and polysaccharides from Marshmallow roots: cellular internalisation and stimulation of cell physiology." J Ethnopharmacol. PubMed
  6. Wu, K.L. et al. (2008). "Effects of ginger on gastric emptying and motility in healthy humans." Eur J Gastroenterol Hepatol. PMC
  7. Morgan, A.G. et al. (1979). "Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin." Gut. PubMed
  8. Salvatore, S. et al. (2000). "A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease." Aliment Pharmacol Ther. PubMed
  9. Park, S.B. et al. (2014). "Meta-analysis of the turnover of intestinal epithelia in preclinical animal species and humans." Drug Metab Dispos. PubMed
  10. van der Flier, L.G. & Clevers, H. (2009). "Stem cells, self-renewal, and differentiation in the intestinal epithelium." Annu Rev Physiol. PubMed
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare provider before starting any supplement regimen, especially if you are pregnant, nursing, or have a medical condition.
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